http://www.grokdotcom.com/usability-of-color.htm “If the ability to distinguish color is a critical element of your site’s persuasion architecture, then your site isn’t as user-friendly as it could be. And it won’t be persuading some folks as effectively as it could.”
Not sure what “persuasion architecture” means, but geek speak aside, a stroll through any local mall is a good way to confirm any doubts around the general public’s abilities with color. Not to say that I’m much better - I seem to end up looking at any given pair of socks in three different light sources before deciding if they are blue or black.
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